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Previous by Date: Subject: BOC clevage safety protocols Date: Thu, 23 Sep 2010 18:38:34 -0700 Author: Russell Vernon |
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My first question is: where was the PPE? As for a written protocol, I would include working within a VBE (vent. balance enclosure), gloves and safety glasses... I am certain others here have more feedback... Sincerely, george George D. McCallion Chemist III Chemical Process Research & Development Johnson Matthey Pharmaceutical Materials 2003 Nolte Drive West Deptford, NJ 08066-1742 Voice: 856.384.7255 Fax: 856.384.7186 E-Mail: medchem**At_Symbol_Here**comcast.net ************************************************************************ ********* On Sep 23, 2010, at 9:38 PM, Russell Vernon wrote: > Dear Fellow Chemists, > > A researcher at one of our sister campuses was using a needless > syringe filled with a solution of 36 mL TFA, 2 mL thioanisole, 1.2 > mL ethane dithiol, and 0.8 mL anisole, She inadvertently expelled a > portion which impacted her elbow. She very quickly washed the > exposure with copious water. The skin became seriously discolored > and it is likely the treatment will include skin grafts. > > This isn=92t my area of expertise but from what I read it is a common > protecting group cleavage cocktail for protein synthesis. > > If any of you have any written procedures that would improve the > process we would appreciate getting a copy. > > Sincerely, > -Russ > > > Russell Vernon, Ph.D. > Research Safety > Environmental Health & Safety > University of California, Riverside > 900 University Ave > Riverside, CA 92521 > www.ehs.ucr.edu > russell.vernon**At_Symbol_Here**ucr.edu > > Direct (951) 827-5119 > Admin (951) 827-5528 > Fax (951) 827-5122
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