My understanding is that sensitization is a stepwise process so a person is exposed and builds antibodies to the sensitizing agent. So the fact that there was no previous reaction to the earrings does not mean it is attributable to the nano form. It could just be that the nickel in the nano cause the sensization to appear. Bob Hill
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-----Original Message-----
>From: Rita Kay Calhoun
>Sent: May 20, 2014 1:35 PM
>To: DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU
>Subject: Re: [DCHAS-L] Occupational handling of nickel nanoparticles: A case report
>
> The original report indicated that one of the reactions she had was to her earrings. This suggests that previously she had had no reaction to the nickel in the earring posts, so the sensitization does appear to be related to the material being in nano form.
>Just a guess.
>Kay
>
>
>-----Original Message-----
>From: DCHAS-L Discussion List [mailto:dchas-l**At_Symbol_Here**MED.CORNELL.EDU] On Behalf Of Ralph B. Stuart
>Sent: Tuesday, May 20, 2014 12:34 PM
>To: DCHAS-L**At_Symbol_Here**MED.CORNELL.EDU
>Subject: Re: [DCHAS-L] Occupational handling of nickel nanoparticles: A case report
>
>> Does the report indicate that the exposure was exacerbated the material being in the nano form?
>
>The report is based on a single case and the fact that the symptoms arose after work with Ni nano-particle began; she had previously worked with non-nano Ni. For a particular incident, I'm not sure how you would determine whether the nano aspect exacerbated the situation. It's more of a suggestive data point report than a conclusive study...
>
>- Ralph
>
>Ralph Stuart CIH
>Chemical Hygiene Officer
>Department of Environmental Health and Safety Cornell University
>
>rstuart**At_Symbol_Here**cornell.edu